What is Dihydromyricetin (DHM)?

Introduction:

Dihydromyricetin, also known as Ampelopsin, and often shortened to DHM is a chemical compound found in a variety of Raisin tree species (Hovenia Dulcis) of all things! For centuries it has been used in all kinds of herbal remedies in Korean, Japanese, and Chinese culture. It had often been used as a treatment of liver problems and to supposedly stop or prevent getting, “too drunk.” Recent studies have found, DHM may have some very useful medical uses for the liver and potentially be a key to reducing intoxication from alcohol as well as post-drinking illness (hangovers).

 

DHM and the Liver

In a randomized study it was found that DHM can work wonders at helping reduce the negative health effects of fatty liver disease (in this case, instances specifically NOT related to alcohol intake). The study was published in 2015 and discussed how glucose and lipid levels dramatically improved in study participants who were given doses of DHM, and the inflammation of their liver was reduced to an impressive degree as well. Simply put, Dihydromyricetin, stimulated certain bodily functions that don’t occur as well when fatty liver disease afflicts someone and did a great job of assisting with insulin resistance. With further testing DHM may have a multitude of uses for liver-related diseases and its success at impacting glucose levels could have a wide range of possible uses in treating certain types of diabetes.

 

DHM and a Reduction in Alcohol Intoxication

Alcohol is the most commonly abused substance in the World. Whether someone is in fact an alcoholic or just drinks too much on some occasions and gets a bad hangover, alcohol intoxication can bring with its a whole lot of sickness. That is why it is exciting how a study in 2012 that has since been expanded upon with similar results found a lot of promising data in regards to DHM reducing alcohol intoxication. Essentially, the study drew-upon lore about DHM as an herb capable of reducing hangovers and when with distilled chemical compounds people taking enough of it could have the intoxicating effects of alcohol countered to some degree as well as a stark reduction in post-intoxication sickness AKA less of a nasty hangover. It was observed that depending on the dose-level different results could be achieved, so someone who wants to have some drinks but not get too drunk or be sick the next day could potentially benefit from distilled doses of DHM and an alcoholic taking higher doses who finds drinking provides less pleasure will then find DHM to be a useful tool in reducing or eliminating their alcohol intake.

 

In Closing: DHM Carries Much Potential!

As initial studies that are now being followed-up on have illustrated, Dihydromyricetin/DHM has a great deal of potential to assist with medical concerns from fatty liver disease to helping in the treatment of alcohol addiction and/or reducing the occurrence or severity of hangovers. DHM is a chemical with a lot of potential and it is interesting to see how a fruity herb that for centuries was thought to be medically useful now has been proven to indeed do just what the ancient herbalists theorized.

 

In a trial of sixty patients with fatty liver disease, dihydromyricetin improved glucose and lipid metabolism and exerted anti-inflammatory effects.

 

Dihydromyricetin shows promise as an alcohol anti-intoxicant.
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NCBI: Dihydromyricetin As A Novel Anti-Alcohol Intoxication Medication
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292407/

 

Wikipedia: Ampelopsin, also known as Dihydromyricetin
https://en.wikipedia.org/wiki/Ampelopsin

Names
IUPAC name

(2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
Other names

Dihydromyricetin, Ampeloptin,(+)-Ampelopsin,(+)-Dihydromyricetin
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